Saturday, February 18, 2012

Provide a plausible explanation for the difference in fitness of the AA genotype in the different environments?

Humans in parts of central Africa with the AS genotype have higher fitness than neighbors with an AA genotype. Humans living on the fringes of the Sahara desert in Africa with an AA genotype has a higher fitness than neighbors with an AS genotype.Provide a plausible explanation for the difference in fitness of the AA genotype in the different environments?AS - sickle cell trait confers increased resistance to malaria so will confer an advantage in central Africa where there is much malaria and so will have a higher fitness.

AA - normal, will have a higher fitness in those areas, such as Sahara desert, where the prevalence of malaria is very low and so the condition of sickle trait has no advantage.
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